Nanofluidic systems

COLL 423

Harold G. Craighead, Applied & Engineering Physics, Applied & Engineering Physics, Cornell University, Clark Hall, Ithaca, NY 14853-2703
By controlling the time and spatial dependence of electric fields one can drive, sort and separate molecules by a variety of physical mechanisms. Time varying electric fields can be used in conjunction with spatially generated free energy barriers to create high-speed molecular sorting systems, exploiting the ability of nanostructures to apply controlled femtoNewton forces on molecular ensembles. With these nanosystems we can control the application of small forces on molecules and observe the response in motion through confined geometries. These approaches give us access to molecules in a way that may enable their separation based on mechanical or other properties. Fluid systems have also been used to deposit nanowires on surfaces. The ability to integrate these with lab-on-a-chip systems and microfluidic systems may be exploited for new types of devices. Related fabrication approaches have been used to create regions of confined optical excitation in 3 dimensions using metallic nanoconstrictions. These devices enable practical studies of biochemical processes at the single molecule level.
 

Adamson Award Symposium Honoring Dave Allara and Ralph Nuzzo

Division of Colloid and Surface Chemistry
The 225th ACS National Meeting, New Orleans, LA, March 23-27, 2003