COLL 43 |
| Kenneth A. Polse1, Meng C. Lin1, Kimberly Miller1, and Clayton J. Radke2. (1) School of Optometry, University of California, Berkeley, 525 Minor Hall, Berkeley, CA 94720-2020, (2) Chemical Engineering Dept, University of California, Berkeley, UCB Campus, Gilman Hall, #101, Berkeley, CA 94720-1462 |
| Ocular complications from contact lens wear (CLW) are caused by a combination of metabolic (i.e., corneal hypoxia) and mechanical factors (i.e., lens-cornea interactions). When lenses are worn during sleep, accumulated metabolic debris is removed after eye opening by tear mixing from lid-induced lens motion. We hypothesize that a low clearing rate of tears after eye opening allows debris to remain sandwiched between the lens and eye, causing corneal trauma, and therefore timely removal of debris is a prudent requirement for safe CLW. In this paper we report tear mixing estimates obtained from currently available and experimental lens designs and use these results to examine a recently reported mixing model which suggests that increased transverse lens movement reduces tear clearing times under the lens. Our engineering-clinical collaboration has been valuable in developing lens designs to optimize tear mixing during contact lens wear. |
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ACS Award in Colloid and Surface Chemistry Symposium Honoring Clay Radke
Division of Colloid and Surface Chemistry |