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UPCOMING EVENTS
MARK YOUR CALENDAR

WNY - ACS

Fall 2003 Dinner Meeting Schedule

Tuesday September 9, 2003
Michael Detty from UB will speak on Photodynamic Light Therapy.
Our 50-Year members who could not attend the Schoellkopf dinner
will be honored, and we'll also have fun door prizes - don't miss it!
Check further down the page for information on location of meeting
and dinner selection

Wednesday October 8, 2003
Ange Fatta from BuffLink will speak on "Creating a Life Sciences Economy in Buffalo Niagara."

Thursday November 6, 2003
Ken Jonmaire from Buffalo State College will speak on a forensics-related topic.

Thursday December 11, 2003
Holiday Meeting, speaker to be announced

Officers and Staff:

 EDITORIAL

Patricia DePra Springsteen
p.springsteen@verizon.net
716-835-1612

REACT

Contact Mary Jean Sryek @ 894-2128
If you have any questions about this organization  

please contact
Dr. Joseph F. Bieron @ 716 888-2357

ISSUE COPY DEADLINE: FIRST OF MONTH PRIOR TO PUBLICATION

The Western New York Section of the American Chemical Society and its editors assume no responsibility for the statements and opinions advanced by the contributors. Views expressed in the editorials are those of the authors and do not necessarily represent the official position of the Western New York Section of the American Chemical Society. All materials to appear in the next issue of the Double Bond must be received by the Editor, in care of the Chemistry Department, Canisius College, 2001 Main Street, Buffalo, New York 14208, by the FIRST day of the month. Notice for change of address should be sent to the editor.

The Double Bond is published monthly from September through June by the WNY Section of the ACS. USPS# 893 86000. Subscriptions: $3/yr. Member subscriptions are included in the annual dues. Advertising rates upon request. Permission to reprint is granted all ACS publications. Office of printer and publication: Canisius College, Buffalo, NY 14208. Postmaster: Send change of address to: P.O. Box 187, Grand Island, NY 14072. Periodical class postage rates at Grand Island, NY 14072-0187.

E-MAIL : dblbond@canisius.edu
WEB PAGE: www.canisius.edu/~dblbond

Good news - Overall Assessment of our Local Section 2002 Annual Report by the Local Section Activities Committee: Western New York is an active and viable Local section with good member participation that reaches out to all in the Section community. You have a very attractive and functional web site. Beautiful! Self-nominations for "Most Innovative New Activity or Program in a Local Section," "Outstanding High School Student Program Award”, "Most Original Hands-on Activity," "Best Student Affiliate Event," and "Local Section Award for Innovative Initiatives in Polymer Sciences." Good job and good luck!

Congratulations to our Younger Chemists Committee powered by UB graduate students and to the Student Affiliate Section at Canisius College. Because of these dynamos, our Local Section has been selected as a finalist for the following ChemLuminary Awards:

* National Chemistry Week Task Force -- Best Student Affiliate Event
* Younger Chemists Committee -- Most Creative Local Section Younger Chemists Committee Event Award
* Younger Chemists Committee -- Outstanding Local Section Younger Chemists Committee Award

Recipients will be announced and the presentation of awards will be at the 226th ACS National Meeting in New York, NY on Tuesday, September 9, 2003 at New York's Hotel Pennsylvania in the Penntop Ballroom. The presentations will include awards given by 14 committees and divisions of the Society. Prior to the ceremony there will be a one-hour poster session in the Skytop Ballroom (adjacent to the Penntop Ballroom). David Nalewajek, our National Chemistry Week Committee Chair, will be our section representative, and will present a poster of these 2002 activities that led to our selection as a finalist. Congrats for an outstanding year!

July 25, 2003
MEMORANDUM

SUBJECT: Important Information Regarding 2003 ACS Fall National Election The deadline for petition candidates for the 2003 ACS Fall National Election was July 15. The official candidates for ACS National Office are:

For President-Elect, 2004
William F. Carroll, Jr., Occidental Chemical Corporation
Michael E. Strem, Strem Chemicals, Incorporated

For Directors-at-Large, 2004-2006
Dennis Chamot, National Research Council
Nancy B. Jackson, Sandia National Laboratory
Peter C. Jurs, Pennsylvania State University
James P. Shoffner, Columbia College

For Director District I, 2004-2006
Ronald D. Archer, University of Massachusetts
Anne T. O'Brien, Wyeth Research, Retired
Dorothy J. Phillips, Waters Corporation

For Director District V, 2004-2006
Judith L. Benham, 3M Company
E. Ann Nalley, Cameron University

Title: Photodynamic Therapy: Using Light to Kill Cancer Cells

Abstract: Photodynamic therapy is a relatively recent addition to the anti-cancer arsenal that uses a light source, a photosensitizer, and the oxygen found in tissues to produce a cytotoxic response. The photosensitizer is excited by wavelengths of light that more readily penetrate tissue (wavelengths between 600 and 900 nm) and the excited state of the photosensitizer reacts with oxygen to produce superoxide (from the singlet excited state) or singlet oxygen (from the triplet excited state). These reactive oxygen species cause the cellular damage. The design of photosensitizers must address structural features that help localize the photosensitizer in or around the tumor tissue and that help provide the proper photophysics. We have been actively studying core-modified porphyrins - porphyrins in which one or both N-H groups in the pyrrole rings are replaced with S, Se, or Te - as photosensitizers. These molecules have long wavelength absorption bands at 700 nm, generate singlet oxygen with quantum yields of > 80%, and are effective both in vitro and in vivo against murine Colo-26 cells (implanted tumors). Systematic variation of substituents has provided a model for optimizing uptake and efficacy.

Bio: for Michael Detty:
B. Sc. - 1972, Chemistry, Bowling Green State University, Bowling Green, Ohio
Ph.D. - 1977, Organic Chemistry with Leo Paquette, The Ohio State University, Columbus, Ohio
1977-1994 - Research Associate, Eastman Kodak Company, Rochester, New York, Synthesis and design of infra-red absorbing dyes and photoconductors,heterocyclic chemistry
1995 to present - Department of Chemistry, University at Buffalo, Buffalo, New York, Current Title Professor of Chemistry

Title of Talk: "Photodynamic Therapy: Using Light to Kill Cancer Cells"

Speaker: Michael Detty, Professor of Chemistry, UB

Date: Tuesday, September 9, 2003

Place: The Eagle House Restaurant
           5578 Main St., Williamsville, NY 14221

Cash Bar: 6:00 PM Cash Bar

Dinner: 6:30 PM 3 meal choices @ a cost of $25.00 each
1) NY Strip Steak Onion Rings
2) Chicken Marsala
3) Fillet of Salmon
Each entrée includes minestrone soup, chef salad, roasted potatoes and freshly baked rolls.

Reservations: Patty at 888-2340 by Friday, September 5, 2003

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Contact

Canisius College Press
Phone: 716-888-3254
FAX: 716-888-3112
E-Mail bieron@canisius.edu
Website: www.canisius.edu/historyproject

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