Double Bond - October 1998

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Double Bond
October 1998



Speaker



Topic:

Mechanistic Studies of Prominent Synthetic Reactions:

Speaker:

Dr. David Hughes
Merck Research Laboratories

Date:

Thursday October 22, 1998

Place:

The Eagle House Restaurant
5559 Main St., Williamsville, NY

Fellowship:

6:00 PM Cash Bar

Dinner:

7:00 PM 3 meal choices @ a cost of $14.00 per person
(1) Open Sliced Top Round of Beef w/ Mushroom Sauce
(2) Roast Turkey Dinner w/Stuffing
(3) Penne Pasta tossed w/olive oil


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Editorial


I was unable to attend the September 22nd meeting. From what I have heard, the talk was extremely interesting and informative. Dr. Vivian Cody, Senior Research Scientist and Head of the Molecular Structure and Drug Design Group at the Hauptman-Woodward Medical Research Institute, gave an excellent presentation entitled ñUse of Virtual Reality and Computer Modeling Tools, Structure-based Drug Design of Antipneumocystis Agentsî. Approximately twelve attended the meeting, enjoyed fine food at The Eagle House Restaurant in Williamsville, asked many great questions and spent a considerable amount of time informally discussing this timely topic.

As many of you know, I have been working with David Roll, Chair of the Rochester Section of ACS, and discussing possible dates for a joint meeting between our sections. He is extremely interested in a joint meeting but recognizes that both sections have standard programs (Job fairs, National Chemistry Week activities, holiday dinners, awards ceremonies, etc.) that must be completed. Until we accomplish a joint meeting, I will continue to share Double Bonds with David and remind him that Rochester ACS members are welcome at all of our dinner meetings.

Any suggestions for other local organizations (A&WMA, IChE, IFT, IEEE, etc.) that may be interested in co-sponsoring or presenting at a chemistry-related meeting of general interest would be greatly appreciated. If you know of anyone that I should contact, please call me at 542-5492.

The next meeting of the Executive Committee will be on Wednesday, October 7th at 7:00 PM at UBÍs Amherst campus. The meeting will take place, as usual, in Room 306 of the Natural Science and Mathematics Complex. I hope to see many of you there.

Mike

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About our Speaker:


Dr. David Hughes is Senior Investigator with 16 years in the Process Research department at Merck, Rahway, NJ. His research interests: Physical organic chemistry, reaction mechanisms, and use of enzymes in organic synthesis. He has 47 publications and 15 patents to his credit. His doctoral work was at Northwestern with Professor Bordwell and he did a post-doc at Duke with Professor Arnett.

Abstract:


Development of an efficient process for a neurokinin receptor antagonist will be presented, focusing on introduction of three chiral centers. As an outgrowth of this project, mechanistic studies on the Petasis-Tebbe olefination were undertaken and will be discussed. The mechanism proposed in the literature is inconsistent with the results of this work.

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The ACS Continuing Education Department
Opens Virtual Campus On The Internet


Washington, DC (September 1998): The American Chemical Society (ACS) Continuing Education Virtual Campus opens up this month at www.uol.com /acs. While ACS continues to offer its popular program of Short Courses, this new Web-based service affords an added benefit to chemical scientists and technicians. It provides greater access to quality continuing education programs for ACS members and others in the scientific community thanks to the worldwide accessibility of the Internet.

Harold Walsh, the assistant director for continuing education for ACS, explained his reasons for developing Internet-based courses: ñWe hope to reach chemists who are not able to travel to attend Short Courses or who simply prefer to take courses at their own offices or homes. Companies are going to have a great deal more flexibility in the training they can offer their employees, because these courses can be accessed any time of the day or night from any place with an Internet connection.î

The first course offered on the campus is Basic Statistical Analysis of Laboratory Data, developed by two renowned ACS Short Course instructors, Stanley N. Deming and Stephen L. Morgan. The course is completely interactive with on-line exercises designed to help the student gauge his or her progress at every step of the way. The information presented is based on practical examples that are found in typical chemistry laboratories. Also included is the opportunity to participate in on-going discussion forums and interact with the instructors and other chemistry professionals who are taking the on-line course.

The ACS Virtual Campus Web site is hosted by UOL Publishing, Inc., a leading publisher of high quality, interactive, Web-based courseware delivered through the Internet to the education and training market.

For answers to other questions about the ACS Virtual Campus, send your e-mail to shortcourses@acs.org .

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State University of New York at Buffalo

OxChem Chemistry Colloquia
Fall Semester 1998
Fridays in Room 205 NSM Complex at 4:00 PM

Refreshments in Room 306 NSM Complex at 3:30 PM *unless otherwise noted

October 9

Professor Lynn Francesconi, Hunter College
Rare Earth Complexes of Polyoxoanions

October 15

Professor Michael Fried, Pennsylvania State University Medical Center
(Joint with Biology) Physical Mechanisms in Gene Regulation

October 16

Professor Carlos R. Cabrera, University of Puerto Rico
Title to be announced

October 23

Professor Bernhard Schlegel, Wayne State University Exploring Potential Energy Surfaces for Chemical Reactions Using Ab Initio Molecular Orbital Calculations

October 30

 Professor James Cowan, Ohio State University
(Joint with Biology) Metals and Nucleic Acids. New Perspectives on Nuclease Chemistry and Drug Design

Physical Organic Minisymposium (supported by UB Conferences in the Disciplines)

November 6

(2:00-6:00 pm)
Professor Peter Wan, University of Victoria
Photochemical Methods for the Generation of Quinone Methides

Professor Andrew Bennet, Simon Fraser University
Homoallylic Carbenium and Nitrenium Ions: Structure Reactivity Correlations

Professor Joseph Lambert, Northwestern University
New Organosilicon Molecules

Professor Charles Perrin, University of California, San Diego
Symmetry of Hydrogen Bonds in Solution

November 13

 Dr. Bradley Coltrain, Eastman Kodak Co.
Organic-Inorganic Composite Films

November 20

 Professor Michael Gross, Washington University
Mass Spectrometry in Peptide and Protein Chemistry: Biophysical and Bioanalytical Application of H/D Exchange

December 4

 Professor Thomas Kalman, University at Buffalo
Mechanism-Based Inhibition of Thymidylate Synthase

Schedule subject to change. Call 716-645-6800 for rescheduled or cancelled seminars.
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ACS Store goes Online with Local Section and Division Award Products

 In April of this year, ChemCenter, the one-stop Web site for chemical professionals in industry, academe, and government worldwide, of the American Chemical Society, went online to bring itÍs members many ACS branded items at reasonable prices, with the convenience and safety of ordering through the Internet. Now the ACS Store has added a new catalog of items especially for Local Sections and Divisions to use in their recognition efforts.

Stop by ChemCenter at http://www.ChemCenter.org and check out the new Local Section and Division Awards catalog. This portion of the ACS Store features plaques, banners, certificates, past-chair pins and ACS emblems to make ordering your recognition items as easy as a few keystrokes and mouse clicks! All prices include shipping and will be delivered to your door via UPS.

For more information on ChemCenter or the ACS Store, visit the web site at http://www.ChemCenter.org or call 1-800-227-5558.


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1998 Chemical Engineering Graduate Research Symposium


Department of Chemical Engineering
University at Buffalo (UB)
State University of New York (SUNY)
October 21, 1998
Student Union, Room ***
North (Amherst) Campus

3:00-4:00pm
Dr. Norman Wagner, University of Delaware
Seminar on"Liquid Crystalline Polymers (LCP) and LCP-Containing Blends"

4:00-4:15pm
Dr. Carl R. F. Lund, Chairperson
Overview of the UB Chemical Engineering department

4:15-5:30pm
Poster Session
All chemical engineering graduate students will participate. The ongoing research activities in the department will be showcased. Faculty will also be available for discussion. Wine and cheese will be served.

5:30pm
"Best Poster" Award and Closing Remarks
For more information feel free to contact any of the members of the organizing committee

P. Alexandridis tel: (716) 645-2911 x2210
S. Andreadis tel: (716) 645-2911 x2204
A. Gupta tel: (716) 645-2911 x2221
S. Neelamegham tel: (716) 645-2911 x2220
M. Swihart tel: (716) 645-2911 x2205
***Room TBA Contact Darlene Innes @ 645-2911 x2202***


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A Cyberspace Science Milestone: All ACS Journals Now on the 'Net


The launch of 25 Web editions means new features, greater comprehensives, and flexibility for subscribers.

The ACS Publications Division has announced that-for the first time-Internet editions of all 25 of its prestigious journals are available. Officially launched at the ACS National Meeting in Las Vegas, these Web versions include interactive features not available in the print journals and a wide range of subscription options.

"We're providing our members and other scientists with what they've been asking for-Web access to all our journals," said Robert Bovenschulte, director, ACS Publications. "Few, if any, other scientific publishers can match the combination of new features, comprehensives, and flexibility we offer on the Web."

The ACS Web editions contain:

Two separate formats to view articles: interactive text (HTML) and complete page image (.pdf). Users can search and print articles from the entire database starting from 1996 to the present.

Interactive links to other recognized databases. These include Medline, the Protein Database, GenBank, and Chemport.

Articles ASAP (as soon as published). Beginning in January 1998, ACS will post journal articles on the Web as soon as they have been peer reviewed, copy edited, and checked by authors for accuracy. That will allow subscribers to see "published" articles several weeks before they appear in the pages of a printed journal.

"The editions come with flexible pricing, so subscribers pay only for as much or as little information as they need," said Bovenschulte.

For ordering and price information call 1-800-333-9511 or 1-614-447-3671, or travel to the ACS home page and click on "About Electronic Editions" at http://pubs.acs.org.


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Senior Chemists

 If you need any information please call:
Emil (Inde) Inderbitzen

636-7885

Hank Heubusch

632-0346



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26th Ontario-Quebec

Physical Organic Symposium
University at Buffalo, Department of Chemistry
Friday November 6 - Sunday November 8, 1998

Keynote Lectures will be given by the following (Friday 2 - 6 pm):

Professor Andrew Bennet (Simon Fraser University)
Professor Joseph Lambert (Northwestern University)
Professor Charles Perrin (University of California, San Diego)
Professor Peter Wan (University of Victoria)
The registration fee will be waived for students from Buffalo institutions! For more details please contact Tina Amyes at tamyes@acsu.buffalo.edu. To register online please visit the conference website at the following URL:

http://wmv.chem.buffalo.edu/poms/

Tina L. Amyes tamyes@acsu.buffalo.edu
Department of Chemistry (716) 645 6800 ext 2195
University at Buffalo, SUNY (716) 645 6963 (FAX)
Buffalo, NY 14260-3000

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R.E.A.C.T.


Date: Oct. 31, 9:00 AM-12:00 Noon Location: Canisius College Building Horan OÍDonnell, Room S-015 Speaker Dave Copeland Chair of Education Committee, Waste Management Topic: TBA Date: Nov. 21, Location: TBA Topic: Chemistry Activities, hands on, and demonstrations UB Graduate Chemistry Club Date: Dec. 12 Topic &Location will be announced

If you need any information please call:

Karen Arnold 884-5894 (one week prior to workshop)




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